The Threat Wheel organizes 21st century health security threats by the strength of the Medical Countermeasures Portfolios available. The threats and categories are listed below:
- Very Strong Medical Countermeasures Portfolio
- Anthrax
- Smallpox
- Plague
- Tularemia
- Strong Medical Countermeasures Portfolio
- Botulism
- Radiological
- Nuclear
- Nerve Agents
- Medical Countermeasures Portfolio Under Development
- Vesicants
- Ebola Zaire
- Glanders
- Melioidosis
- No Medical Countermeasures Exist
- Ebola Sudan
- Marburg
- Pharmaceutical Based Agents
- Chlorine
- Cyanide
- MDR Anthrax
- Unknown Threats