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U.S. Department of Health and Human Services

2015 PHEMCE Strategy and Implementation Plan

The United States continues to face a range of serious threats to its national health security from the deliberate use or accidental release of chemical, biological, radiological, and nuclear (CBRN) agents, as well as from naturally occurring and emerging infectious diseases (EID), including pandemic influenza.

Cover of the 2015 HHS Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) Strategy and Implementation Plan Under the leadership of the Department of Health and Human Services (HHS), the Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) is the coordinating body for the federal agencies in charge of protecting the civilian population from potential adverse health impacts of these threats through the use of medical countermeasures (MCMs). These MCMs include medicines, devices, or other medical interventions that can lessen the harmful effects of both intentional and naturally emerging threats.

To ensure that our priorities reflect current scientific progress and fiscal capabilities, the PHEMCE annually assesses and updates a PHEMCE Strategy and Implementation Plan (SIP) to ensure optimal allocation of resources to address high-priority threats. As required by section 2811(d) of the Public Health Service (PHS) Act , as amended by
section 102 of the Pandemic and All-Hazards Preparedness Reauthorization Act (PAHPRA), a PHEMCE  SIP is released annually. The 2015 PHEMCE Strategy and Implementation Plan (SIP) is a streamlined document that updates the 2014 PHEMCE SIP, the blueprint for the PHEMCE to enhance national health security through the development, procurement and planning for effective use of critical MCMs.


The 2015 PHEMCE SIP reflects HHS’s continued commitment, in collaboration with its interagency PHEMCE partners, to provide the nation with a nimble, flexible capacity to rapidly produce and effectively use medical countermeasures in the face of any attack or threat whether known or unknown, novel or reemerging, natural or intentional.

The 2015 PHEMCE SIP reaffirms the goals and objectives that were established in the 2014 PHEMCE SIP. It also describes new activities to be pursued, in addition to those included in the 2014 PHEMCE SIP, to increase MCM preparedness for national health security threats. New activities focus particularly on emerging infectious diseases, Ebola preparedness and response, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and the National Strategy for Combating Antibiotic-Resistant Bacteria (CARB).

Information in the 2015 PHEMCE SIP includes:

  • Summary of major accomplishments since the 2014 PHEMCE SIP
  • New activities now being pursued by the PHEMCE agencies A summary of PHEMCE interactions with non-federal stakeholders
  • Progress in addressing the needs of at-risk populations
  • A summary of advanced research and development and procurement awards
  • Information regarding the use of funds and authorities originally authorized and provided by the Project BioShield Act of 2004

  • This page last reviewed: December 22, 2015