Skip Ribbon Commands
Skip to main content
Skip over global navigation links
U.S. Department of Health and Human Services

Promising Practices for Public Health Professionals

Healthcare professionals walking through a hospital unit.


The following documents provide promising practices and recommendations from provider organizations and state public health programs that increased the utilization of COVID-19 monoclonal antibody treatments.

These findings provide inspiration and information to those working to build treatment awareness and demand and can supplement individual plans and provide context to playbooks and planning discussions with leadership.

  • Applying a Risk-Adapted Strategy: Intermountain Healthcare’s Monoclonal Antibody Treatment Program: Intermountain Healthcare used a risk-adapted strategy to identify COVID-19 patients who were likely to benefit from monoclonal antibody treatment. With this risk-adapted approach, Intermountain Healthcare was able to prioritize high-risk patients and decrease the risk of being hospitalized with severe illness. Uniquely, Intermountain Healthcare applied an equity lens to their risk-adapted strategy by including data about geographic location, race, ethnicity, and gender.

  • Effectively Using Data: Maryland's Statewide Monoclonal Antibody Infusion Program: The Maryland Department of Health developed a data-driven initiative to bring monoclonal antibodies to high-risk COVID-19 patients across the state. Monoclonal antibody infusions were made accessible to hard hit and underserved communities - 7,210 patients were treated from December 2020 to April 2021 (a 33% increase). As of April 2021, it is estimated that about 338 hospitalizations were avoided, and 139 deaths prevented because of Maryland’s efforts.

  • Engaging Many Partners: Michigan’s Statewide Monoclonal Antibody Infusion Program: Michigan was able to significantly increase monoclonal antibody use during a major surge this past spring through proactive support from senior state officials; mobilizing paramedics, nurses, and pharmacists; establishing reporting and performance metrics; and repurposing existing case investigation software to connect patients with infusion sites.

  • Enhancing Communication: Grand View Medical Practices and TriValley Primary Care Collaboration for Monoclonal Antibody Treatment: A hospital-owned primary care practice and a community hospital with a 200-bed capacity collaborated to develop a centralized communication system and protocol to quickly track high-risk COVID-19 patients with monoclonal antibodies. The protocol, which prioritized access to and timeliness of treatment, was shared via preexisting communication channels with the community of practices served by the hospital, and resulted in smooth implementation of treatment and dissemination of information for both providers and patients.

  • Providing Equitable Access to COVID-19 Monoclonal Antibody Treatment: Teche Action Clinics in southwest Louisiana, the County of San Diego and the Black Coalition Against COVID were all successful in connecting patients with monoclonal antibody treatments by establishing, maintaining, and expanding trust through community building; amplifying testimonials and strategic outreach; and providing education in the context of each community’s specific needs to successfully implement patient-centered approaches to care.

  • This page last reviewed: October 01, 2021