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U.S. Department of Health and Human Services

Category: Innovations

Lessons from Fukushima: New guide provides answers to save lives and improve emergency medical response

Author: John F. Koerner, MPH, CIH, Senior Special Advisor - Chemical, Biological, Radiological, Nuclear, High-Yield Explosive (CBRNE) Science and Operations, HHS ASPR Immediate Office
Published Date: 3/12/2018 2:22:00 PM
Category: Public Health Preparedness; Innovations; Exercises & Trainings; Hospital Preparedness; National Health Security; Response & Recovery;

Quick questions: A nuclear incident has occurred in your community and people are going to come to you for help. Do you know which medical issues you should focus on first? Or which steps need to be taken immediately after an incident to best protect the public? Or what resources might be available to help?

Before you answer “no” to any of those questions, download a copy of the newly released Decision Maker’s Guide: Medical Planning and Response for a Nuclear Detonation.

An e  Read more…

Aging and Disability Task Force: An Access and Functional Needs Approach to Addressing the Unmet Disaster Needs Following Hurricanes Irma and Maria

Author: Cheryl A. Levine, Ph.D., Senior Policy Analyst & Team Lead for At-Risk Individuals; Jose Velasco, MSW, Public Health Analyst for At-Risk Individuals; and Amit Zigelman, MPH, Jr. Management Analyst, Aveshka, Inc. in support of the ASPR Division for At-Risk Individuals, Behavioral Health & Community Resilience
Published Date: 2/21/2018 4:42:00 PM
Category: Response & Recovery; Public Health Preparedness; Innovations;

The recent impacts of Hurricanes Irma and Maria left Puerto Rico and the U.S. Virgin Islands (USVI) in complete devastation. Buildings and homes were destroyed. Hospitals, dialysis centers, and pharmacies that weren’t destroyed were closed due to water and wind damage or a lack of electricity. Transportation services were lacking or, in some areas, non-existent. These issues affected everyone; however, people with access and functional needs – including older adults and people with disabilities – were particularly vulnerable in the hurricanes’ aftermath.

In response, the Off  Read more…

BARDA Supports a Rapid, Deployable, Sensitive Diagnostic Platform to Diagnose Anthrax

Author: HHS/ASPR Biomedical Advanced Research and Development Authority
Published Date: 11/20/2017 1:55:00 PM
Category: Medical Countermeasures; Innovations; Public Health Preparedness;

In the wake of an anthrax attack, medical responders need to quickly determine who has been infected so that they can be effectively treated. A rapid, accurate diagnostic test is an essential tool for doctors and other health professionals to effectively triage people who may be infected with anthrax. Such a tool has been long requested by medical responders as a critical component of anthrax preparedness.

On September 27, 2017, BARDA awarded a $3,199,221 base period of a contract to Tangen BioSciences Inc. of Branford, CT to further advance and expand the ability to combat  Read more…

BARDA adds new antibiotic to treat drug-resistant bacterial infections in order to protect the American public

Author: Mark Albrecht, Project Officer, Biomedical Advanced Research and Development Authority, HHS Office of the Assistant Secretary for Preparedness and Response
Published Date: 8/30/2017 1:21:00 PM
Category: Medical Countermeasures; Public Health Preparedness; Innovations; National Health Security;

Antibiotics underpin nearly every facet of modern medicine. You can’t have a hip replacement or a caesarean section without effective antibiotics to prevent or treat bacterial infections. The same holds true in a mass public health emergency involving a chemical, biological, radiological or nuclear (CBRN) threat. During a biodefense emergency, people may be hospitalized for prolonged periods, potentially exposing them to secondary infections including drug-resistant infections that are occurring at an alarming rate.

That’s why BARDA is focused on development and approval of  Read more…

Whatever it takes: Medical Reserve Corps volunteers leverage eastern tradition to aid behavioral health after disasters

Author: Stacy Sayre, Region 8 Medical Reserve Corps Liaison and Rachelle Lambert, Licensed Acupuncturist and Unit Coordinator, Colorado Acupuncture Medical Reserve Corps
Published Date: 8/16/2017 9:41:00 AM
Category: Response & Recovery; Public Health Preparedness; Innovations;

After the terrorist attacks of September 11, 2001, managers at St. Vincent’s Hospital in New York asked the nearby Lincoln Recovery Center to provide respite and ear acupuncture treatment for staff and first responders impacted by the tragedy. Some of those treated reported that after treatment they slept better than they had in days or weeks.

Lincoln Recovery had developed an ear acupuncture treatment called the NADA protocol to assist substance abuse detoxification and recovery support in concert with other behavioral health interventions. The successful use of this techni  Read more…

New Frontiers and Extreme Environments: BARDA and NASA Join Forces to Better Protect the American Public and Astronauts from Radiation Injury

Author: Mary J. Homer, PhD, Chief of Radiological and Nuclear Countermeasures Branch, HHS/ASPR/BARDA and Lynne Wathen, Biodosimetry Team Leader in the Diagnostics and Medical Devices Division, HHS/ASPR/BARDA
Published Date: 8/2/2017 10:22:00 AM
Category: Medical Countermeasures; Innovations; Public Health Preparedness;

Although an odd couple at first glance, NASA and the Biomedical Advanced Research and Development Authority in the office of the HHS ASPR share a common interest: protecting people from radiation injury.

  Read more…

EMS Infectious Disease Playbook: Combatting Infectious Disease Threats with Knowledge and Best Practices

Author: Jennifer Nieratko, ASPR TRACIE Team; John Hick, MD, Emergency Physician and Deputy Chief EMS Medical Director, Hennepin County Medical Center & HHS; and Richard Hunt, MD, Senior Medical Advisor, National Healthcare Preparedness Programs, HHS/ASPR Office of Emergency Management
Published Date: 6/26/2017 10:58:00 AM
Category: Public Health Preparedness; Innovations;

Emergency medical services (EMS) providers face a wide variety of risks on an almost daily basis, ranging from physically dangerous scenes and combative patients or bystanders to inattentive drivers to the negative behavioral health effects of exposure to traumatic incidents. While EMS personnel cannot predict which hazard they may face on any given day, the entire EMS community – medical directors who establish policies and procedures, dispatchers who direct personnel to patients, and responders at a scene – has a stake in staying up-to-date on innovations in the field and related  Read more…

Powering the next generation of antibacterial innovation to enhance national security

Author: Tyler Merkeley, MS, MBA, CARB-X Program Manager, BARDA
Published Date: 3/30/2017 11:50:00 AM
Category: Public Health Preparedness; Medical Countermeasures; Innovations; National Health Security;

It’s about the people. Picture a worried mother from Arizona walking into the hospital with her 11-year-old daughter. The girl had gone from tired to intense hip pain and a high fever in just a few days. A blood test revealed a potentially fatal condition called sepsis from a Staphylococcus infection. The infection had begun as an abscess in her hip muscle, spread into her blood, and eventually caused a devastating antibiotic-resistant bacterial pneumonia in her lungs.

Mom sat day-in and day-out watching her daughter’s health rapidly fade; tubes ran all over her body, and a   Read more…

Strengthening the Links in Disaster Supply Chain Management

Author: Laura K. Wolf, Ph.D., Branch Chief, Critical Infrastructure Protection Branch, Office of Emergency Management, HHS ASPR
Published Date: 2/1/2017 4:52:00 PM
Category: Innovations; Public Health Preparedness;

When you are responding to a pandemic flu outbreak, you don’t just need a safe and effective vaccines and antivirals – you also need syringes and other medical supplies so that they can be administered.  Sounds simple, but supply chain issues caused serious problems during the responses to the H1N1 influenza outbreak, Hurricane Sandy, and Ebola.

Healthcare and public health systems rely on the availability of products such as pharmaceuticals, laboratory testing supplies, personal protective equipment, and medical devices to care for the American people.  Ava  Read more…

BARDA-supported Zika vaccine candidate enters clinical trial

Author: Rick Bright, Director, Biomedical Advanced Research and Development Authority, HHS Office of the Assistant Secretary for Preparedness and Response (ASPR)
Published Date: 1/9/2017 5:24:00 PM
Category: Innovations; Medical Countermeasures; Public Health Preparedness;

The U.S. government has marked another significant milestone in its effort to better protect Americans against the Zika virus: the first ASPR-supported Zika vaccine has begun a Phase I clinical trial, which will evaluate the general safety of the vaccine in people and provide information on the ways that different doses of the vaccine impact immune response.

The investigational vaccine developed by Moderna Therapeutics of Cambridge, Massachusetts, utilizes a novel messenger RNA (mRNA) vaccine technology. Moderna’s vaccine consists of a small piece of mRNA that when injec  Read more…

Ensuring a coordinated response to Zika and other public health threats

Author: George W. Korch, Jr., Senior Science Advisor, HHS Office of the Assistant Secretary for Preparedness and Response
Published Date: 12/5/2016 12:41:00 PM
Category: Public Health Preparedness; Innovations; Hospital Preparedness; Medical Countermeasures; Response & Recovery;

When the first confirmed case of Zika transmission was reported in Puerto Rico on December 31, 2015, there were no vaccine candidates for Zika. Today there are at least a dozen approaches in the US alone that are being evaluated to someday be available for general use. Diagnostic assays to help patients make informed decisions about their health are also under development.

How have so many medical countermeasures advanced so quickly to fight a threat that few people were worried about just last year?

The partners in the Public Health Emergency Medical Enterprise (PHEM  Read more…

Better preparing for future Ebola outbreaks globally

Author: David Boucher, Health Scientist, ASPR/BARDA’s Division of Chemical, Biological, Radiological, and Nuclear Medical Countermeasures and Dr. Richard Hatchett, acting director, ASPR’s Biomedical Advanced Research and Development Authority
Published Date: 10/13/2016 10:27:00 AM
Category: Public Health Preparedness; Innovations; Medical Countermeasures;

While the Ebola virus disease is not in the news as much now as it once was, we cannot afford to let down our guard. Ebola cases flared up again as recently as this March in West Africa, causing eight deaths in Guinea and one death in Liberia, and more than 30 other outbreaks of the disease have been recorded in the last 40 years.

The Ebola outbreak of 2014-2016 highlighted the urgent need for therapeutics that could increase the survival rate of infected patients and also aid response organizations in their efforts to limit the spread of this deadly virus. ZMapp, developed  Read more…

From the front lines of the anthrax investigation to pre-staging our future health response

Author: Dr. Rick Jaffe, Director, Medical Countermeasures Strategy and Requirements, ASPR’s Office of Policy and Planning
Published Date: 9/29/2016 4:28:00 PM
Category: Innovations; Medical Countermeasures; Public Health Preparedness;

Fifteen years ago this month, anthrax was used as a terrorist weapon against our nation. As a microbiologist with experience in dealing with Bacillus anthracis, the bacteria that causes anthrax illness, I was called in to be on the front lines of the investigation into the attack. Today, I help ensure our nation is best prepared for and can respond to a future one.

Soon after September 11, 2001, an attacker mailed letters laced with anthrax spores causing the deaths of five people and sickening 22 others. As part of the response, I donned a hazmat suit to investigate  Read more…

Anticipating Threats, Investing in Solutions

Author: Brian N. Tse, Ph.D., Health Scientist, Antibacterials Branch, Division of Chemical, Biological, Radiological, & Nuclear Medical Countermeasures, Biomedical Advanced Research & Development Authority (BARDA), HHS Office of the Assistant Secretary for Preparedness & Response
Published Date: 6/7/2016 3:53:00 PM
Category: Innovations; Medical Countermeasures; Public Health Preparedness;

Deadly new strain of bacteria? BARDA’s already working on it.

For the first time, the bacterial gene mcr-1, which confers resistance to the “antibiotic of last resort,” colistin, was found in a bacterium isolated from a patient in the United States  Read more…

Community Paramedicine and the Changing Face of Pre-Hospital Care

Author: Experts from the CMS Innovation Center
Published Date: 5/20/2016 10:59:00 AM
Category: Public Health Preparedness; Response & Recovery; Innovations; Hospital Preparedness;

For decades, emergency medical services (EMS) have conjured an image of ambulances speeding to save a life. We’re all familiar with their customary and important roles: rapid response for those in medical crisis; stabilization at the scene when necessary; and transport to hospital emergency departments (EDs) for continued management. Activated by a national network of 911 call centers, EMS professionals are poised for deployment to almost any site in the country to intervene in an emergency.

Today, however, many EMS systems have evolved from responding to medical emerge  Read more…

Updating the EMS Agenda for the Future: The Search for Data-Driven Approaches to Improvement

Author: Gregg Margolis, Division of Health System Policy, Office of the Assistant Secretary for Preparedness and Response, U.S. Department of Health and Human Services & Tara Holland, GAP Solutions, Inc. - Supporting the mission of the Office of the Assistant Secretary for Preparedness and Response
Published Date: 5/16/2016 4:56:00 PM
Category: Public Health Preparedness; Response & Recovery; Innovations;

The emergency medical services (EMS) community is working to find collaborative solutions to some very tough questions so that they can better provide quality care during disasters and every day. For example, how can EMS professionals quickly access critical medical information on a patient with the current fragmented system of medical records? How can the system surge effectively and pull in people from other states in the face of interstate credentialing requirements? What are the opportunities for EMS to improve community health beyond emergency response?

These are   Read more…

Putting Patients First: Reforming Emergency and Acute Care Delivery in the U.S.

Author: Aisha Hasan, Policy Analyst, Emergency Care Coordination Center, HHS/ASPR Division of Health System Policy
Published Date: 2/25/2016 11:40:00 AM
Category: Hospital Preparedness; Public Health Preparedness; Innovations;

Meet 22-year-old John. He’s visiting his older sister, Ann, on Monday evening when he starts to throw-up and develops severe abdominal pain. John is in pain and Ann is scared. At around 7 p.m., Ann takes him to the urgent care center a block from her apartment.

Due to his persistent vomiting and history of kidney stones, John is sent to the closest emergency department (ED). He typically goes to a different hospital in town closer to his apartment and had a CT scan there last week. There is no health information exchange shared by the competing hospitals. Phone calls to t  Read more…

BARDA seeks to launch a novel partnership, a product accelerator to address antimicrobial resistance

Author: Joe Larsen, Ph.D. Deputy Director BARDA Division of CBRN Medical Countermeasures HHS/ASPR/BARDA
Published Date: 2/19/2016 10:17:00 AM
Category: Innovations; Medical Countermeasures;

Today the Biomedical Advanced Research and Development Authority (BARDA), in collaboration with our colleagues at the National Institutes of Allergy and Infectious Disease (NIAID) released a Funding Opportunity Announcement to establish the Combating Antibiotic Resistant Bacteria (CARB) Biopharmaceutical Accelerator.  The Accelerator represents a novel public private partnership that will support research and development to accelerate candidate products (drugs, vaccines, and diagnostics) into clinical development.

Infections with bacteria that are resistant to e  Read more…

Fighting Antibiotic Resistance: The Long Road to New Solutions

Author: Melissa Stundick, PhD, Chief, Anti-Infectives Program, BARDA & David Simon, PhD, Project Officer, Anti-Infectives Program, BARDA
Published Date: 11/19/2015 3:44:00 PM
Category: Innovations; Medical Countermeasures;

Clinicians have relied on antibiotics to treat bacterial infections ever since they were discovered in the early 20th century. As a result, mortality and hospitalization rates that resulted from common infections went down. So did the Western world’s urgency to pursue alternative methods of fighting bacteria.

Since the discovery of antibiotics, western researchers have instead focused on developing drugs that block an essential enzyme or process that bacteria require to survive or replicate. At first, this approach was successful. Several new classes of antibiotics were dis  Read more…

Staying protected while always connected

Author: Stephen Curren, Director, ASPR’s Office of Emergency Management, Division of Resilience
Published Date: 10/9/2015 3:52:00 PM
Category: Innovations; Public Health Preparedness;

The Internet touches almost all aspects of everyone’s daily life, whether we realize it or not. With a world that’s more connected than ever, cybersecurity matters whether you’re with a government agency or a private company.

Alarmingly, criminal cyberattacks against healthcare organizations are up 125 percent compared to five years ago, replacing lost laptops as the top cause of breaches, according to the Ponemon Institute’s Fifth Annual Benchmark Study on Privacy and Security of Healthcare Data. The survey also showed that the average consolidated total cost of a data bre  Read more…

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