Public Health Emergency - Leading a Nation Prepared
Author: Dr. John Redd – Chief Medical Officer, HHS Office of the Assistant Secretary for Preparedness and Response Published Date: 7/6/2021 1:34:00 PM
Category: Medical Countermeasures; Innovations; Hospital Preparedness; Response & Recovery; Public Health Preparedness;
This week, we announced a new tool that can help hospitals, health care facilities, and other potential infusion sites make smart choices to better manage and reduce COVID-19 related patient surge: the COVID-19 Monoclonal Antibody Therapeutics Calculator (mAbs Calculator).
In some parts of the country, where COVID-19 cases are high and vaccination rates are low, many hospitals continue to face patient surge. Other areas are facing new surges in patients as the Delta variant of the virus spreads in their Read more…
Author: Mark Albrecht, Ph.D., Branch Chief, Anti-Bacterial Program, ASPR/BARDA Division of CBRN Countermeasures; Cameron Bess, Ph.D., Biologist and Project Officer Antibacterials Program, ASPR/BARDA Division of CBRN Countermeasures; and Jessica Swenson, MPH, Program Analyst, Antibacterials Program, ASPR/BARDA Division of CBRN Countermeasures. Published Date: 6/8/2021 7:09:00 PM
Category: Medical Countermeasures; Innovations;
Although the battle against COVID-19 has been a primary focus over the past 16 months, the Biomedical Advanced Research and Development Authority (BARDA) has remained committed to developing solutions against a wide range of other threats as well.
One critical area of focus is the development of antibacterial medical countermeasures to combat antimicrobial resistance (AMR) through a variety of mechanisms including a global accelerator program BARDA co-founded. This non-profit partnership funds early-stage research of innovative and transformational technologies for the diagno Read more…
Author: Gretta Blatner, MPH, Special Assistant to the Director, Biomedical Advanced Research and Development Authority (BARDA), U.S. Department of Health and Human Services (HHS)
; Ashley Cecere, MS, Biologist, Biomedical Advanced Research and Development Authority (BARDA), U.S. Department of Health and Human Services (HHS); Rachel Rath, MBA, MPH, Director, BARDA Alliance, Johnson & Johnson Innovation – JLABS
Published Date: 4/27/2021 10:31:00 AM
Category: Innovations; Medical Countermeasures; Public Health Preparedness;
In what the
Biotechnology Innovation Organization (BIO) is calling a “monumental campaign to combat, and hopefully eradicate, COVID-19,” it’s become evident that small, creative-thinking biotech companies are needed to help lead on the frontline..< Read more…
Author: Sandeep Patel, Ph.D., Director, BARDA Division of Research, Innovations and Ventures, Kumiko Lippold, Ph.D., M.P.H., Health Scientist, BARDA Division of Research, Innovations and Ventures Published Date: 4/8/2021 12:32:00 PM
Category: Innovations; Medical Countermeasures; Response & Recovery; Public Health Preparedness;
The creative talent of inventors and entrepreneurs across the entire country is the heartbeat of our economy and our nation’s well-being. At BARDA, we’d like to tap this energy to solve a critical challenge for our country: the design of comfortable, protective facemasks for the general public. Scientific evidence shows that masks can be useful in curbing the spread of respiratory infections, yet we know that actual use is not up to the same standard as intended use. Research shows the most common reasons people don’t wear masks or don’t wear them properly: fit, comfort – i Read more…
Author: Christopher Houchens, Ph.D., Director, Division of CBRN Medical Countermeasures, Biomedical Advanced Research and Development Authority (BARDA), U.S. Department of Health and Human Services
Marian Nakada, Ph.D., Vice President, Venture Investments, Johnson & Johnson Innovation – JJDC, Inc.
Published Date: 3/17/2021 1:24:00 PM
Category: Innovations; Response & Recovery;
Launching an innovative product or technology takes more than a good idea, and there are many actions startups can take to strengthen their offering and overall chance of success as they develop the latest innovations to bolster health security, including battling COVID-19. Over the last year, the global scientific community has proven critical to our collective ability to combat the pandemic, and Blue Knight™ offers a new way to build the kinds of partnerships needed to advance potentially life-saving technology during public health emergencies.
Blue Knight Read more…
Author: Cheryl Levine, ASPR/EMMO Published Date: 12/28/2020 11:23:00 AM
Category: Response & Recovery; Innovations;
“Alone we can do so little; together we can do so much” – Hellen Keller
If you work for a community-based organization (CBO Read more…
Author: Rick Bright, Ph.D., BARDA Director and Deputy Assistant Secretary for Preparedness and Response Published Date: 1/8/2020 1:32:00 PM
Category: Medical Countermeasures; National Health Security; Public Health Preparedness; Hospital Preparedness; Innovations;
Relatively minor injuries, like a cut that I got while gardening, can quickly become more serious if they become infected with antibiotic-resistant bacteria. Today, doctors often don’t have the diagnostic tests needed to inform patient care, and the tests that do exist may take too long to provide results. Without this vital information, doctors don’t have the information they need to ensure patients are getting the right antibiotics, serve as good stewards of antibiotics to prevent resistance, or when Read more…
Author: Timothy G. Buchman, PhD, MD, FACS, FCCP, MCCM, Subject Matter Expert and IPA to BARDA DRIVe Published Date: 9/18/2019 11:03:00 AM
Category: Medical Countermeasures; Innovations;
Day four of the annual professional meeting began like so many others: I had one more talk to give, and then a dash to the airport for the flight home. At lunchtime, I noticed a slight headache. By the time the session began mid-afternoon, the headache was worse. I bummed a couple of over-the-counter pain pills from a colleague (thank heavens for better prepared friends!), chugged a bot Read more…
Author: Rick A. Bright, Ph.D., BARDA Director Published Date: 8/7/2019 10:53:00 AM
Category: Medical Countermeasures; Innovations; National Health Security;
Project BioShield is revolutionizing the way we protect Americans from 21st century health security threats. Think back almost 18 years ago to the anthrax attacks of 2001. That crisis highlighted just how few medical countermeasures our nation had to respond to a bioterrorism incident. The anthrax attacks taught us important lessons that still guide our thinking: innovation is critical, partnerships matter, and the threats that we face are very real and very serious.
Alth Read more…
Author: By Dr. Robert Kadlec, Assistant Secretary for Preparedness and Response Published Date: 7/17/2019 12:15:00 PM
Category: Innovations; Medical Countermeasures; National Health Security;
Saving lives in a public health emergency requires cutting-edge medical countermeasures: medications, vaccines, diagnostics, and more. In some types of emergencies, like an act of bioterrorism, some of those medical products have no commercial market. People don’t use an anthrax antitoxin every day – thank goodness. Yet that lack of commercial market also means pharmaceutical or biotech companies had only one possible buyer for their products: the federal government for stockpiling.
In 2004, Congress passed the Project BioShield Act to create a market for products Read more…
Author: Rodney L. Wallace, Director, Detection, Diagnostics, and Devices Infrastructure Division, HHS/ASPR Biomedical Advanced Research and Development Authority Published Date: 6/6/2019 10:36:00 AM
Category: Innovations; Medical Countermeasures; Hospital Preparedness;
The first commercially available Zika virus diagnostic, a product BARDA supported through its advanced research and development program, received authorization for marketing from the U.S. Food and Drug Administration (FDA) on May 23. The test provides results from a blood sample in about four hours. Called the ZIKV Detect 2.0 IgM Capture ELISA, the test exemplifies the progress that is possible with public-private Read more…
Author: Robert Kadlec, MD, Assistant Secretary for Preparedness and Response, U.S. Department of Health and Human Services Published Date: 3/14/2019 4:13:00 PM
Category: Public Health Preparedness; Medical Countermeasures; Response & Recovery; Innovations;
Blog Series: Battling the Ebola Epidemic
Ebola reemerged as a health threat in 2018, in the Democratic Republic of the Congo (DRC), where two outbreaks of Ebola virus disease have occurred since May 2018. The first of these two outbreaks, in western DRC, was quickly contained. However, the second outbreak, in eastern DRC, has yet to be contained due in large part to the volatile security situa Read more…
Author: By Ruben Donis, Ph.D., Pandemic Influenza Medical Countermeasures Division, Biomedical Advanced Research and Development Authority (BARDA), HHS Office of the Assistant Secretary for Preparedness and Response (ASPR) Published Date: 12/13/2018 9:13:00 AM
Category: Medical Countermeasures; Innovations; National Health Security;
As part of our nation’s overall pandemic preparedness strategy, HHS set a preparedness goal of establishing and maintaining a stockpile of bulk vaccine antigen and adjuvants for influenza viruses with pandemic potential to vaccinate 26 million people immediately after a pandemic is declared. BARDA began pre-pandemic influenza vaccine procurement in 2005 for vaccines that would provide protection against emerging avian influenza H5N1 viruses posing a significant pandemic threat. But a decade later we were compelled to ask how long would those stored vaccine components Read more…
Author: Robert P. Kadlec, MD, MTM&H, MS, Assistant Secretary for Preparedness and Response, U.S. Department of Health and Human Services and Steven H. Walker, Director, Defense Advanced Research Projects Agency Published Date: 10/1/2018 3:06:00 PM
Category: Innovations; Medical Countermeasures;
On September 18, marking seventeen years since the first anthrax attack in the United States, the President unveiled a National Biodefense Strategy and signed a National Security Presidential Memorandum which directed federal agencies to collaborate on biodefense, including budgets, to make the nation safer.
That spirit of interagency collaboration is reflected in a new partnership forged between ASPR and the Defense Advanced Research Projects Agency – DARPA – to strengthen the capa Read more…
Author: Rick Bright, Director, and Julie Schafer, Acting Director of Strategy, both of ASPR’s Biomedical Advanced Research and Development Authority (BARDA), a component of the Office of the Assistant Secretary for Preparedness and Response (ASPR) Published Date: 7/13/2018 4:20:00 PM
Category: Medical Countermeasures; Innovations; Public Health Preparedness; National Health Security;
In the 20th century alone, smallpox deaths worldwide numbered in the hundreds of millions. Roughly one-third of people infected with the disease died, while survivors were often left with permanent scars or blindness. After an aggressive global vaccination program in the mid-1970s, the World Health Organization declared smallpox eradicated.
But smallpox remains a health security threat in the 21st century. Fears that undeclared stocks of the smallpox virus might exist and that they could be used as weapons of bioterrorism spurred the U.S. government’s Biomedical Advance Read more…
Author: Rick Bright, Director, and Julie Schafer, Acting Director of Strategy, both of ASPR’s Biomedical Advanced Research and Development Authority (BARDA), a component of the Office of the Assistant Secretary for Preparedness and Response (ASPR) Published Date: 5/21/2018 4:56:00 PM
Category: Innovations; Public Health Preparedness; Observances; Medical Countermeasures; National Health Security;
BARDA and its industry partners have made tremendous strides to build better, faster, and more flexible vaccine technologies to enable the right vaccine to be where we need it, when we need it. Combating this age-old problem is an epic challenge, and there is still work to be done to speed availability of life-saving vaccines in a pandemic.
In September 1918, a doctor stationed at Camp Devens, a military base located near Boston, Massachusetts, wrote a letter to a colleague:
Author: Judith Wolfe Laney, PhD, Chief of Chemical Medical Countermeasures, Division of Chemical, Biological, Radiological and Nuclear Countermeasures within BARDA at the Office of the Assistant Secretary for Preparedness and Response Published Date: 4/11/2018 9:31:00 AM
Category: Exercises & Trainings; Medical Countermeasures; Public Health Preparedness; Response & Recovery; Innovations;
Last month, a truck carrying 4,400 gallons of hydrochloric acid collided with a train in Centerville, PA. For several hours, a column of white vapor floated above the wreckage. Emergency responders acted quickly to evacuate residents in the area and clean up the spill.
On a daily basis, thousands of businesses use our nation’s roads and railways to transport hazardous chemicals used for industrial or household purposes. Whether a chemical is released by accident, such as the case in Centerville, or intentionally by rogue assailants, terrorist organizations, or non-state acto Read more…
Author: John F. Koerner, MPH, CIH, Senior Special Advisor - Chemical, Biological, Radiological, Nuclear, High-Yield Explosive (CBRNE) Science and Operations, HHS ASPR Immediate Office Published Date: 3/12/2018 2:22:00 PM
Category: Public Health Preparedness; Innovations; Exercises & Trainings; Hospital Preparedness; National Health Security; Response & Recovery;
Quick questions: A nuclear incident has occurred in your community and people are going to come to you for help. Do you know which medical issues you should focus on first? Or which steps need to be taken immediately after an incident to best protect the public? Or what resources might be available to help?
Before you answer “no” to any of those questions, download a copy of the newly released Decision Maker’s Guide: Medical Planning and Response for a Nuclear Detonation.
An e Read more…
Author: Cheryl A. Levine, Ph.D., Senior Policy Analyst & Team Lead for At-Risk Individuals; Jose Velasco, MSW, Public Health Analyst for At-Risk Individuals; and Amit Zigelman, MPH, Jr. Management Analyst, Aveshka, Inc. in support of the ASPR Division for At-Risk Individuals, Behavioral Health & Community Resilience Published Date: 2/21/2018 4:42:00 PM
Category: Response & Recovery; Public Health Preparedness; Innovations;
The recent impacts of Hurricanes Irma and Maria left Puerto Rico and the U.S. Virgin Islands (USVI) in complete devastation. Buildings and homes were destroyed. Hospitals, dialysis centers, and pharmacies that weren’t destroyed were closed due to water and wind damage or a lack of electricity. Transportation services were lacking or, in some areas, non-existent. These issues affected everyone; however, people with access and functional needs – including older adults and people with disabilities – were particularly vulnerable in the hurricanes’ aftermath.
In response, the Off Read more…
Author: HHS/ASPR Biomedical Advanced Research and Development Authority Published Date: 11/20/2017 1:55:00 PM
Category: Medical Countermeasures; Innovations; Public Health Preparedness;
In the wake of an anthrax attack, medical responders need to quickly determine who has been infected so that they can be effectively treated. A rapid, accurate diagnostic test is an essential tool for doctors and other health professionals to effectively triage people who may be infected with anthrax. Such a tool has been long requested by medical responders as a critical component of anthrax preparedness.
On September 27, 2017, BARDA awarded a $3,199,221 base period of a contract to Tangen BioSciences Inc. of Branford, CT to further advance and expand the ability to combat Read more…
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