Casirivimab (a.k.a. REGN10933) Injection (120 mg/ml)
MUST ADMINISTER WITH IMDEVIMAB (a.k.a. REGN10987)
Manufacturer: Regeneron Pharmaceuticals, Inc.
Distributor: AmerisourceBergen (a.k.a. ABC);
c19therapies@amerisourcebergen.com
Product: Component of 2-drug monoclonal antibody cocktail for outpatient infusion
Emergency Use Authorization (EUA): 11/21/20
Units: Supplied in 2 volumes
- 1332 mg/11.1 ml single-dose vial in carton (10 ml from 1 vial needed for patient course)
- 300 mg/2.5 ml single-dose vials in cartons (10 ml; 2.5 ml from each of 4 vials needed for patient course)
Note: Some cartons and vials of casirivimab may be instead labeled REGN10933 |
Example: 1332 mg/ 11.1 ml carton
Example: 300 mg/2.5 ml carton |
Storage: Keep in carton until use. Unopened vials must be stored at refrigerated temperature (2oC–8oC / 36°F–46°F) until use. Do not freeze, shake, or expose to direct light.
Earliest Expiration Date of Units Shipped: 06/2022
Single Vial w/ Carton Dimensions: 1.7”(d) x 1.8”(w) x 2.8”(h)
Single Vial w/ Carton Weight: 1.5 oz. for 1332 mg/11.1 ml vial; 0.9 oz. for 300 mg/2.5 ml vial
Case: A full case contains 24 vials in cartons
Case Dimensions: 9.6”(d) x 7.4”(w) x 4.6”(h)
Case Weight: 2.7 lb. for 1332mg/11.1 ml vials; 1.8 lb. for 300 mg/2.5 ml vials
Administration: (Detailed guidelines are available.)
- Inject 10 ml (1200 mg) casirivimab
- Inject 10 ml (1200 mg) imdevimab
- Infuse final volume (270 ml) containing cocktail of 2 monoclonal antibodies over at least 60 min
Note: If immediate patient infusion is not possible, store the diluted cocktail solution at refrigerated temperature (2oC–8oC / 36°F–46°F) for no more than 36 hours and at room temperature for no more than 4 hours, including infusion time.
Imdevimab (a.k.a. REGN10987) Injection (120 mg/ml)
MUST ADMINISTER WITH CASIRIVIMAB (a.k.a. REGN10933)
Manufacturer: Regeneron Pharmaceuticals, Inc.
Distributor: AmerisourceBergen (a.k.a. ABC);
c19therapies@amerisourcebergen.com
Product: Component of 2-drug monoclonal antibody cocktail for outpatient infusion
Emergency Use Authorization (EUA): 11/21/20
Units: Supplied in 2 volumes
- 1332 mg/11.1 ml single-dose vial in carton (10 ml from 1 vial needed for patient course)
- 300 mg/2.5 ml single-dose vials in cartons (10 ml; 2.5 ml from each of 4 vials needed for patient course)
Note: Some cartons and vials of imdevimab may be instead labeled REGN10987 |
Example: 1332 mg/ 11.1 ml carton
Example: 300 mg/2.5 ml carton |
Storage: Keep in carton until use. Unopened vials must be stored at refrigerated temperature (2oC–8oC / 36°F–46°F) until use. Do not freeze, shake, or expose to direct light.
Earliest Expiration Date of Units Shipped:06/2022
Single Vial w/ Carton Dimensions: 1.7”(d) x 1.8”(w) x 2.8”(h)
Single Vial w/ Carton Weight: 1.5 oz. for 1332 mg/11.1 ml vial; 0.9 oz. for 300 mg/2.5 ml vial
Case: A full case contains 24 vials in cartons
Case Dimensions: 9.6”(d) x 7.4”(w) x 4.6”(h)
Case Weight: 2.7 lb. for 1332mg/11.1 ml vials; 1.8 lb. for 300 mg/2.5 ml vials
Administration: (Detailed guidelines are available.)
- Inject 10 ml (1200 mg) casirivimab
- Inject 10 ml (1200 mg) imdevimab
- Infuse final volume (270 ml) containing cocktail of 2 monoclonal antibodies over at least 60 min
Note: If immediate patient infusion is not possible, store the diluted cocktail solution at refrigerated temperature (2oC–8oC / 36°F–46°F) for no more than 36 hours and at room temperature for no more than 4 hours, including infusion time.
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