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Public Health Emergency U.S. Department of Health and Human Services

S3 - Science Safety 


Biosecurity, Biosafety, Biocontainment, and Biorisk Management

Welcome to the website of the S3: Science, Safety, and Security program, which addresses biosafety, biosecurity, biocontainment, and biorisk management. 

The S3 program promotes transparency and broader awareness about the evolving nature of biological agents that can be hazardous, and how to handle and use these agents safely and securely. The resources provided here include information for laboratory personnel who work with potentially hazardous biological agents, their supervisors, the management personnel of the institutions in which they work, policymakers, and the public. Learn More >>


Button:  Biosafety Stewardship


Biosafety Stewardship

On August 28, 2104, the White House released a memorandum from Lisa Monaco, Assistant to the President for Homeland Security and Counterterrorism, and John Holdren, Assistant to the President for Science and Technology, calling for enhanced biosafety biosecurity measures.  Learn More >>

Laboratory beakers

Dual Use Research of


Import-Export of Biological Materials


Legal and Policy Framework


Strategies and Reports


Presentations from Select
Agent Programs

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Additional U.S.
Government Resources

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Frequently Asked Questions