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U.S. Department of Health and Human Services

Contract awarded to develop drug to protect against radiation-induced gastrointestinal injury

Date:  September 28, 2011

Company: RxBio Inc. of Johnson City, Tenn.

Contract amount: $15 million over two years

About this contract: RxBio Inc will study the efficacy of its drug Rx100, which may protect against radiation-induced gastrointestinal injury by interrupting programmed cell death, known as apoptosis. Preliminary data suggests that Rx100 can protect or mitigate injury and improve survival if administered up to 72 hours after deadly whole-body radiation exposure. The contract also supports development of manufacturing processes for the drug.

Additional information: BARDA is seeking additional proposals for products that potentially could treat or prevent illness and injury from acute radiation syndrome, as well as improved diagnostic tools to measure the radiation dose a person has absorbed after a nuclear denotation or radiation accident.  Proposals are accepted through the Broad Agency Announcement BARDA-CBRN-BAA-11-100-SOL-00009 at

Press Release:  BARDA funds development of five drugs to protect against radiation

Procurement Announcement:  Contract Awarded under BAA-BARDA-09-34

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  • This page last reviewed: January 11, 2018